In this assay I will discuss the paintings of modern female artist, Jenny Saville, consider the gender-fluid and gender/sexuality conflict emerged by artist's operation of materials about gender/sexuality. Savill plays an important role in the art of modern female body and transgender. For Saville, the system of medical treatment and the surgical experiences inspired her to create the modern body appearances, which provide a chance for reconsider the relation of the plastic surgery, the system of medical treatment, and the gender theory. The scalpel could not govern the essence of gender/sexuality and gender construct; the body represented under the system of medical treatment also could not suture the subject represented. Furthermore, modern femalists re-link the identity to the body experiences as support for female identity politics, but at the same time negate the mental experiences of the subject of transgender.